The fourth installment of Joanne Burke’s critically acclaimed NEW DIRECTIONS series on women's empowerment in developing countries, SPEAKING OUT presents a compelling case study on the impact of AIDS on women from Mali and the devastating effects the epidemic is having in Africa today. This critically acclaimed documentary profiles a remarkable HIV and AIDS support project in Bamako, Mali, sponsored by The Center for Care, Activity and Council for People Living with HIV (CESAC), and three brave women who tirelessly work on behalf of the infected community. Risking social ostracism and family rejection, Aminita, Oumou and Aissata are among a small group who dare to speak publicly about their HIV+ status. They help others with HIV, particularly women, by joining AFAS, the women's association for the support of widows and children of AIDS. Through their advocacy work they hope to demonstrate to the Mali government the desperate need for a more pro-active HIV and AIDS strategy. With the help of CESAC, these inspiring women are proving that an HIV+ diagnosis is not the end of life, but the start of a positive future for all African men and women.